CELEBREX 200MG CAPSULE contains Celecoxib which belongs to group of medicines called Non-steroidal anti-inflammatory drugs. CELEBREX 200MG CAPSULE is used in adults to manage osteoarthritis (degenerative joint disease), rheumatoid arthritis (inflammatory disease of joints), ankylosing spondylitis (chronic back pain), acute pain and primary dysmenorrhea (menstrual cramps).
CELEBREX 200MG CAPSULE is also used to manage juvenile rheumatoid arthritis (in children aged 2 years and above).
CELEBREX 200MG CAPSULE is not recommended for use in patients allergic to Celecoxib, sulfonamides, aspirin and/or other NSAIDs. It is also not recommended for use in patients with/had a history of an ulcer in stomach/intestines, bleeding in stomach/intestines, blood circulation problems (such as peripheral arterial disease), red itchy welts, inflammatory disease of the intestines (such as ulcerative colitis/Crohn’s disease).
The medicine is also not indicted for use in patients suffering from lung problems (such as asthma), heart diseases (such as heart failure, recent heart attack, heart block), severe liver disease (such as advanced hepatic insufficiency) and/or kidney disease (such as advanced renal insufficiency).
Before taking CELEBREX 200MG CAPSULE, inform your doctor if you have diabetes, raised blood pressure, increased cholesterol, signs of fluid retention (such as swollen ankles and feet) and/or hyperkalemia (increased potassium level in blood).
CELEBREX 200MG CAPSULE is not recommended for use in pregnant and breast-feeding women.
CELEBREX 200MG CAPSULE should be used with caution in children and adolescents (aged 2 to 17 years) to manage only juvenile rheumatoid arthritis and is advised to be used with caution in elderly patients (aged 65 years/above) after consulting the doctor.
The most common side effects of taking CELEBREX 200MG CAPSULE are high blood pressure, shortness of breath, sore throat, cough, headache, nausea and dizziness. Consult your doctor if any of these symptoms worsen.
How should I take CELEBREX 200MG CAPSULE? CELEBREX 200MG CAPSULE comes in tablet or capsule form:CELEBREX 200MG CAPSULE should be taken:
umerous pills every 30 minutes ( 40 mg CELEBREX)
Fioriterol:
Consider consulting your doctor if your doctor does not believe your condition and is allergic to any ingredients
How often should I take CELEBREX 200MG CAPSULE? Before starting CELEBREX 200MG CAPSULE, inform your doctor about your medical history, especially the following:CELEBREX 200MG CAPSULE can cause temporary light sensitivity of the skin especially on the upper body. Use caution when talking to your doctor. CELEBREX 200MG CAPSULE may increase signs and symptoms of cardiovascular problems (such as heart attack, stroke, heart failure, blood pressure decrease). Inform your doctor if you are losing or maintaining your weight. Ask your doctor before taking CELEBREX 200MG CAPSULE if you are: older women, patients with phenylketonuria (a significant mental weakness), patients with history of seizures, seizures with rapid cycling. Before using CELEBREX 200MG CAPSULE, tell your doctor your medical history
Before having surgery, tell your doctor about your medical history:
During surgery, CELEBREX 200MG CAPSULE is associated with increased risk of various types of cancers (such as breast, uterine, prostate and soft tissue and lung), including deep ones (ijuana) and oncology (cyalis) – all of which can be serious.
The most common side effects of celebrex (Celebrex) are muscle pain, joint pain, and fatigue. In fact, about 30% of patients with rheumatoid arthritis also experience some side effects.
The most commonly reported side effects of Celebrex include:
Celebrex can also cause a serious form of bone loss called osteoporosis. It is not recommended for people with osteoporosis.
If you experience any of the above serious side effects, speak with your doctor. Celebrex is not a cure for osteoporosis, but a form of treatment.
If you are pregnant, trying to become pregnant, or breastfeeding, tell your doctor right away. In some cases, you may need to discontinue the drug, which may affect your baby. Do not stop taking Celebrex abruptly without speaking to your doctor. Stopping the drug suddenly can cause your baby’s body to lose all its usual strength.
If you experience any of the above serious side effects, please call your doctor immediately.
Celebrex belongs to a class of drugs called atypical antipsychotics. They are usually given to people with psychiatric disorders, such as schizophrenia or bipolar disorder.
These drugs are also used for purposes not listed in this medication guide.
The recommended starting dose of Celebrex for osteoporosis is 10 mg to 40 mg per day. The maximum recommended dose is 40 mg per day.
This medication is available only with a doctor’s prescription. Celebrex comes as capsules and oral liquid. It is not to be taken by mouth or by swallowing pills.
Celebrex should not be taken with blood thinners, such as warfarin, aspirin, or corticosteroids, and it is contraindicated for people with a history of bleeding or thromboembolic disorders. Celebrex may also interact with some medications, such as theophylline, ibuprofen, and aspirin.
Celebrex can cause serious side effects in people with certain medical conditions. Tell your doctor if you are pregnant, plan to become pregnant, or are breastfeeding. Tell your doctor immediately if you experience severe nausea, vomiting, diarrhea, or rash. In these cases, stop taking Celebrex and contact your doctor immediately.
The recommended starting dose of Celebrex for osteoporosis is 10 mg to 20 mg per day. The maximum recommended dose is 20 mg per day.
Celebrex is not to be taken by mouth or by swallowing pills. It should be taken with food at least 15 minutes before the activity of a certain drug is expected to begin. This will help to avoid stomach upset.
Celebrex can cause serious side effects in people with a history of bleeding or thromboembolic disorders.
Celebrex is a medication that has been used to treat pain for a variety of reasons, including arthritis, and is also an anti-inflammatory medication.
Celebrex is a drug that belongs to a class of medications called NSAIDs. NSAIDs work by temporarily blocking your body's production of certain natural substances that cause pain. This helps lower your risk of side effects such as stomach pain, heartburn, and other stomach issues.
Celebrex may also be used to treat a condition that affects the lining of the small intestine (stomach lining) or to prevent the narrowing of the tube that carries stool through the stomach. This can be caused by an injury to the lining of the intestine, for example, an intestinal obstruction, or a tumor in the lining of the intestine.
If Celebrex is used to treat pain or inflammation, it can be used to reduce the risk of stomach ulcers. Celebrex is also used to prevent the development of heart attacks and strokes, especially if you have high blood pressure or are taking certain other medicines. This is because Celebrex can cause a serious allergic reaction when it comes to aspirin.
Celebrex may also be used to treat heart failure. It is sometimes used to treat high blood pressure (BP). This is because it can lower blood pressure by reducing the amount of a certain blood clot that the body can carry.
It is important to talk to your doctor about whether Celebrex is safe and effective for you if you have heart problems or heart disease. Your doctor will likely be able to tell you whether Celebrex is safe for you if you have heart disease or heart failure.
Celebrex is not known to be safe for people with certain medical conditions, including stomach ulcers, which can cause bleeding. It is also not known if Celebrex is safe for people with a certain type of bleeding disorder.If you take Celebrex or any other medication for a condition such as arthritis, your doctor will likely recommend it for you. They may also need to adjust the dose of Celebrex or take special precautions to ensure the safest use of the medication.
Celebrex may also be used to treat stomach ulcers, such as peptic ulcers, caused by an infection, or a bleeding disorder caused by a bacteria called Helicobacter pylori. Celebrex is also sometimes used to prevent ulcers caused by ulcer medications such as Zantac and Celebrex.
Celebrex is available in both oral and topical forms. Prescriptions for Celebrex are very low, but it is important to talk to your doctor about the possible risks and benefits of using it. In general, Celebrex is considered safe for most people with stomach problems.If you are taking Celebrex for pain and inflammation, your doctor will likely recommend you take it for the treatment of pain and inflammation. The medication may also be used to prevent the development of heart attacks and strokes.
It is not known if Celebrex is safe for you or if there is a risk of heart problems when you use this medication.
You should talk to your doctor about your treatment with Celebrex.
You should not take Celebrex if you have a history of stomach problems such as ulcers, bleeding disorders, or bleeding in the stomach, ulcers caused by ulcers or bleeding in the stomach, or bleeding caused by bleeding from a certain injury to the stomach or intestines. This is because Celebrex may cause an allergic reaction, which can range from mild to life threatening. In rare cases, Celebrex can cause a serious allergic reaction that can affect any part of the body, including the face, mouth, tongue, throat, skin, and the eyes. This reaction may include symptoms such as itching, swelling, and difficulty breathing.If you have been prescribed Celebrex for pain and inflammation, your doctor will likely recommend it for you.
You should talk to your doctor about whether or not you should take Celebrex or any other medication for pain and inflammation. They will likely be able to tell you whether or not Celebrex is safe for you if you have heart problems or heart disease.
You should talk to your doctor about whether you should take Celebrex for the treatment of your pain and inflammation.
You should talk to your doctor about whether or not you should take Celebrex for the treatment of your pain and inflammation.Celebrex (celecoxib) is a nonsteroidal anti-inflammatory drug (NSAID) used to treat inflammatory conditions such as rheumatoid arthritis and osteoarthritis [
,
]. Celecoxib has demonstrated significant efficacy for reducing pain, inflammation, and stiffness caused by these conditions [
The efficacy of Celecoxib in reducing pain and inflammation was demonstrated in a randomized, double-blind, placebo-controlled trial involving 884 patients with rheumatoid arthritis and 763 non-stomachic patients with osteoarthritis [
Celecoxib was also shown to reduce pain and increase the stiffness of rheumatoid arthritis, in patients with musculoskeletal conditions. The main objective of this study was to compare the efficacy and safety of Celecoxib versus non-steroidal anti-inflammatory drugs (NSAIDs) in reducing pain and inflammation. The objective of the study was to compare the efficacy and safety of celecoxib versus non-steroidal anti-inflammatory drugs (NSAIDs) in reducing pain and inflammation.
The participants were divided into two groups, celecoxib and placebo, in a double-blind, placebo-controlled trial. Both groups received a standard dose of celecoxib for at least one week before the scheduled procedure. Celecoxib was administered in the morning, while the placebo group received an equivalent dose of celecoxib, in a randomized, double-blind, placebo-controlled trial [
The patients with osteoarthritis were given Celecoxib at baseline and the same dose of placebo for a minimum of 30 minutes before the procedure. The procedure was performed for 2 weeks, and the patients were randomized to receive celecoxib at the dose of 100 mg, 200 mg, or 400 mg in one of four equal-sized double-blinded and placebo-controlled randomized clinical trials:
1.1. Randomization: Patients with a body weight between 25 and 35 kg were randomly assigned to receive Celecoxib 100 mg, 200 mg, or 400 mg in a single randomization block of 3 d. The randomization order was a 1:1 combination of placebo, Celecoxib 100 mg, Celecoxib 200 mg, and placebo. Patients with a body weight of more than 50 kg were randomly assigned to receive Celecoxib 200 mg, while patients with a body weight of less than 50 kg were randomly assigned to receive Celecoxib 100 mg.
2.2. Study Design
The study was a double-blinded, placebo-controlled, randomized trial. Patients with rheumatoid arthritis were enrolled in the study and the study medication was administered in the morning. Patients were excluded from the study if they were:
Participants had no medical history of rheumatoid arthritis (including rheumatoid factor and other related conditions);
1.2. Patients had an active peptic ulcer;
1.3. Patients were excluded from the study if they had a history of gastrointestinal bleeding, asthma, a history of peptic ulcers, ulcer-associated colitis, a history of gastrointestinal bleeding, or other gastrointestinal conditions such as severe liver disease, and patients who had anemia or hypochlorhydric acidemia;
1.4. Patients had received NSAIDs (e.g., COX-2 inhibitors) before the procedure;
1.5. Patients with a history of gastrointestinal bleeding, asthma, or a history of peptic ulcers were excluded from the study.
Compared with celecoxib, there was a statistically significant reduction in pain scores, as shown in
Figure 1. Change in scores from baseline, after celecoxib and placebo were administered.
The mean reduction in pain scores was statistically significantly higher for celecoxib than for placebo (P < 0.01). In addition, there was a statistically significant difference in the number of pain-related events (P < 0.01) between celecoxib and placebo in the first 6 weeks of treatment (Figure 1).
The mean number of days from baseline to the end of the study was 7.0 in celecoxib and 7.6 in placebo groups.